Peptide Database

Peptide NameTachykinin-related peptide 8

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Tachykinin peptide

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC59H100N22O16S2

DescriptionStandard

        QERRAMGFVGMR
    

Molecular Weight1437.69 Da

Isoelectric Point (pI)11.70

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.56

Charge Density (pH 7.0) 0.1469

GRAVY Index-0.72

Hydrophobic Moment 0.27

Boman Index-0.34

Instability Index59.59

Aliphatic Index 32.50

Aromaticity 0.0833

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 649.51

LogP -6.66

H-bond Donors 24.0

H-bond Acceptors 20.0

Rotatable Bonds 50.0

Heavy Atoms 99.0

Ring Count 1.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0015267 VERIFIED: YES

Provenance & Taxonomy

OrganismRhodnius prolixus [Animal]

FamilyTachykinin-related peptide

Tax ID13249

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Neuromodulator Myotropic

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0339923 VERIFIED: YES

Provenance & Taxonomy

OrganismRhodnius prolixus [Animal]

FamilyTachykinin

Tax ID13249.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Other ModsPyroglutamylated isoform reported: pyro-QERRAMGFVGMR

Bio-Activity Profile

Function

Neuropeptide

MethodLC-MS/MS

RECORD: Rec_0347681 VERIFIED: NO

Provenance & Taxonomy

OrganismRhodnius prolixus [Animal]

FamilyTachykinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

-

RECORD: Rec_0397923 VERIFIED: YES

Provenance & Taxonomy

OrganismRhodnius prolixus [Animal]

FamilyTachykinin

Tax ID13249

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Tachykinin Neuropeptide Neuromodulator