Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length108 amino acids

Chemical FormulaC516H831N143O151S8

DescriptionStandard

        MGEKVSKEKWVTPAVRTLTILAAILLVALQAQAEPLQARGDEVAAAPEQITADNPEVVVSLAWDESLAPKDSGSRKNMACACRIPLCLAGERRYGTCFYLGRVWAFCC
    

Molecular Weight11710.51 Da

Isoelectric Point (pI)6.23

Net Charge (pH 7.0)-0.54

Net Charge (pH 7.4) -0.87

Charge Density (pH 7.0) -0.0050

GRAVY Index0.13

Hydrophobic Moment 0.65

Boman Index0.08

Instability Index46.86

Aliphatic Index 94.07

Aromaticity 0.0648

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4683.95

LogP -43.35

H-bond Donors 168.0

H-bond Acceptors 159.0

Rotatable Bonds 380.0

Heavy Atoms 818.0

Ring Count 16.0

Amide Bonds 113.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0069084 VERIFIED: NO

Provenance & Taxonomy

OrganismNomascus leucogenys [Bacterium]

FamilyDefensin

Tax ID61853

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence