Peptide Database

Peptide NameCathelicidin antimicrobial peptide [Cleaved into: Antibacterial peptide FALL-39 (FALL-39 peptide antibiotic); Antibacterial peptide LL-37]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length170 amino acids

Chemical FormulaC838H1363N235O254S7

DescriptionStandard

        MNTQWDSPSLGRWSLVLLLLGLVMPLAIVAQVLSYQEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTIQRSPEECDFREDGLVKWCVGTVTLNQAKDSFDISCDKDKRKVAQLGDVLQKAGEKIVRGLKNIGQRIKDFFGKLTPRTES
    

Molecular Weight19018.66 Da

Isoelectric Point (pI)7.60

Net Charge (pH 7.0)0.48

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0028

GRAVY Index-0.33

Hydrophobic Moment 0.84

Boman Index-0.07

Instability Index40.71

Aliphatic Index 92.82

Aromaticity 0.0588

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7922.18

LogP -84.83

H-bond Donors 276.0

H-bond Acceptors 262.0

Rotatable Bonds 639.0

Heavy Atoms 1334.0

Ring Count 23.0

Amide Bonds 183.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0213650 VERIFIED: YES

Provenance & Taxonomy

OrganismAteles fusciceps [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-MRSA Antibiofilm Antifungal Anti-Candida Anti-Gram-negative Hemolytic

TargetEscherichia coli

RECORD: Rec_0219892 VERIFIED: YES