Peptide Database

Peptide NameLausporin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC72H107N15O16

DescriptionStandard

        FLSALWGVAKSLF
    

Molecular Weight1438.71 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0584

GRAVY Index1.38

Hydrophobic Moment 0.40

Boman Index0.56

Instability Index19.47

Aliphatic Index 127.69

Aromaticity 0.2308

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 494.79

LogP -1.00

H-bond Donors 18.0

H-bond Acceptors 17.0

Rotatable Bonds 44.0

Heavy Atoms 103.0

Ring Count 4.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0381334 VERIFIED: YES

Provenance & Taxonomy

OrganismLiocheles australasiae [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Other ModsAPD analysis reveals that this sequence is similar (76.92%) to scorpion VmCT1 L: 23%; F=S: 15%; GRAVY: 1.38; M Wt: 1438.731; M formula: C72H108N15O16; mol ex coeff: 5550, pI: 8.75. Chemical modification: C-terminal amidation

Bio-Activity Profile

Function

Antimicrobial

Targetincluding antibiotic-resistant strains, Gram- Escherichia coli ATCC 25922 or ATCC 35218

Activity20-80 μg/mL

MethodMIC

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