MYP_031006
halicylindramide B
Antimicrobial
Venom / Toxin
▸
General toxin
▸
Toxin
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
XXPVXWRXTXFTNG
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0316164
VERIFIED: YES
Provenance & Taxonomy
Halichondria cylindrata [Animal]
halicylindramide
Structure & Mods
side-chain cyclized peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Formylation
Lactonization with threonine
Non-proteinogenic/modified monomers: D-NFo-Ala; Br-Phe; t-Leu; D-CysA; NMe-Gln
Bio-Activity Profile
Cytotoxic
Anticancer
Antifungal
Antimicrobial
Toxin
P388 murine leukemia cells
0.2 μg/mL
IC50
RECORD: Rec_0433292
VERIFIED: YES
Provenance & Taxonomy
Halichondria cylindrata [Animal]
halicylindramide
Structure & Mods
side-chain cyclized peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Formylation
Lactonization with threonine
Non-proteinogenic/modified monomers: D-NFo-Ala; Br-Phe; t-Leu; D-CysA; NMe-Gln
Bio-Activity Profile
Antifungal
Antimicrobial
Cytotoxic
Toxin
Mortierella ramanniana
7.5 μg/disk
antifungal disk assay