Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length194 amino acids

Chemical FormulaC985H1499N229O294S9

DescriptionStandard

        IDDLAEIDYSLNSLPTVLQPFIDLDLKGIVYPAGSYSGPPYVAAPFTIPDQSDSMLYLAFSEYFFQTCSFAYYTAGAFNITIAEEVSRIQRNGWLRTCSFFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIINLEQDSFTAEIQGSMEVFAVLPDSTTHSLFTMNIAANTSIALNIFDQKLMGSLCLNR
    

Molecular Weight21541.38 Da

Isoelectric Point (pI)4.17

Net Charge (pH 7.0)-12.16

Net Charge (pH 7.4) -12.50

Charge Density (pH 7.0) -0.0627

GRAVY Index0.28

Hydrophobic Moment 0.75

Boman Index0.23

Instability Index47.25

Aliphatic Index 96.08

Aromaticity 0.1289

Extinction Coeff. Reduced 20400.00

Extinction Coeff. Oxidized 20525.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8275.62

LogP -94.71

H-bond Donors 283.0

H-bond Acceptors 292.0

Rotatable Bonds 685.0

Heavy Atoms 1517.0

Ring Count 39.0

Amide Bonds 209.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0285620 VERIFIED: NO

Provenance & Taxonomy

OrganismPelecanoides urinatrix (Common diving petrel) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria