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MYP_030877
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Basic Information
DPV10/6
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C96H183N47O25
Standard
Sequence
SRRARRSPRESGKKRKRKR
Physicochemical Analysis
2395.78 Da
12.00
10.46
10.24
0.5505
-3.04
0.77
-1.38
179.33
5.26
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1275.60
-18.25
51.0
36.0
90.0
168.0
1.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0068293 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
DPV/CAP37-derived
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Cys addition for conjugation
None
N-term detail: Cys added to N -terminus for conjugation of report
Bio-Activity Profile
Cell-penetrating peptide
HeLa; HCT116; HL-60; K562; Molt4; NIH-3T3; primary hepatocyte cultures
Cellular uptake assay
PMID15859953 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15859953/
RECORD: Rec_0208015 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Cys addition
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID15859953 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15859953/
RECORD: Rec_0338762 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Cys addition
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID15859953 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15859953/
RECORD: Rec_0383865 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
DPV
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Cysteine addition
None
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PaperNovel human-derived cell-penetrating peptides for specific subcellular delivery of therapeutic biomolecules PMID15859953 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15859953/
RECORD: Rec_0394722 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Cys addition
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID15859953 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15859953/