Peptide Database

Peptide Namebeta-Defensin, DEFB5

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC166H284N58O51S6

DescriptionStandard

        ESCKLGRGKCRKECLENEKPDGNCRLNFLCCRQRI
    

Molecular Weight4100.78 Da

Isoelectric Point (pI)8.93

Net Charge (pH 7.0)3.78

Net Charge (pH 7.4) 3.51

Charge Density (pH 7.0) 0.1081

GRAVY Index-1.02

Hydrophobic Moment 0.46

Boman Index-0.45

Instability Index28.96

Aliphatic Index 55.71

Aromaticity 0.0286

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1836.60

LogP -22.02

H-bond Donors 70.0

H-bond Acceptors 61.0

Rotatable Bonds 146.0

Heavy Atoms 281.0

Ring Count 2.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0150604 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-30; 10-24; 14-31

Bio-Activity Profile

Function

Antimicrobial