Peptide Database

Peptide NameAntimicrobial protein CAP18 (18 kDa cationic protein) (18 kDa lipopolysaccharide-binding protein) (CAP18-A) [Cleaved into: Antimicrobial protein CAP7]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length171 amino acids

Chemical FormulaC888H1414N248O251S7

DescriptionStandard

        METHKHGPSLAWWSLLLLLLGLLMPPAIAQDLTYREAVLRAVDAFNQQSSEANLYRLLSMDPQQLEDAKPYTPQPVSFTVKETECPRTTWKLPEQCDFKEDGLVKRCVGTVTRYQAWDSFDIRCNRAQESPEPTGLRKRLRKFRNKIKEKLKKIGQKIQGFVPKLAPRTDY
    

Molecular Weight19804.69 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)7.66

Net Charge (pH 7.4) 7.23

Charge Density (pH 7.0) 0.0448

GRAVY Index-0.62

Hydrophobic Moment 0.72

Boman Index-0.13

Instability Index46.28

Aliphatic Index 79.30

Aromaticity 0.0877

Extinction Coeff. Reduced 29450.00

Extinction Coeff. Oxidized 29700.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8089.44

LogP -82.65

H-bond Donors 282.0

H-bond Acceptors 268.0

Rotatable Bonds 658.0

Heavy Atoms 1394.0

Ring Count 34.0

Amide Bonds 185.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0060221 VERIFIED: YES

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyCathelicidin

Tax ID9986

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Non-hemolytic

TargetGram-negative bacteria