Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length154 amino acids

Chemical FormulaC750H1193N213O222S6

DescriptionStandard

        MAISKNMKAFLDMLAYSEGTDNGRQKTNNHGYDVIVGGSLFTDYSDHPRKLISLPKLGIKSTAAGRYQVLAKFYDAYKKQLRLPDFSPASQDAIAMQLIRECKATADIEAGRIADAIHKCRSRWASLPGAGYGQHEQKLDKLIQVYKEAGGAVA
    

Molecular Weight16938.18 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)5.83

Net Charge (pH 7.4) 5.34

Charge Density (pH 7.0) 0.0379

GRAVY Index-0.40

Hydrophobic Moment 0.68

Boman Index-0.04

Instability Index33.22

Aliphatic Index 80.65

Aromaticity 0.0844

Extinction Coeff. Reduced 17420.00

Extinction Coeff. Oxidized 17545.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7040.83

LogP -71.02

H-bond Donors 246.0

H-bond Acceptors 238.0

Rotatable Bonds 573.0

Heavy Atoms 1191.0

Ring Count 23.0

Amide Bonds 165.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0047894 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage C1 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic