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MYP_030765
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Basic Information
RJ5
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C99H191N33O22
Standard
Sequence
AKKAAKKAKKAAKKAKKAAKK
Physicochemical Analysis
2195.78 Da
11.04
11.78
11.58
0.5611
-1.46
0.71
-0.59
9.52
42.86
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
957.56
-9.18
34.0
34.0
89.0
154.0
0.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0211203 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
Herpes simplex virus 1 (Replication); MRC-5
41 μM
Plaque assay
PaperA wide range of medium-sized, highly cationic, alpha-helical peptides show antiviral activity against herpes simplex virus. | Jenssen H, Andersen JH, Mantzilas D, Gutteberg TJ. | Antiviral Res. 2004 | PMID:15498607 PMID15498607 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15498607/
RECORD: Rec_0214895 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 15498607 PMID15498607 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15498607/
RECORD: Rec_0331920 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 71.4%, E 0.0%, T 19.0%, C 9.5% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0346843 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
herpes simplex virus 2(HSV-2):inhibition of HSV-2 infection in MRC-5 cells
14.3 μM
IC50
PaperPubMed PMID: 15498607 PMID15498607 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15498607/
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