Peptide Database

Peptide NameZ-YVAD-FMK

Function Ontology

Binding / Molecular interaction ▸ Binding activity

Binding / Molecular interaction ▸ Protein-protein interaction

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length4 amino acids

Chemical FormulaC21H30N4O8

DescriptionStandard

        YVAD
    

Molecular Weight466.48 Da

Isoelectric Point (pI)4.30

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.3091

GRAVY Index0.30

Hydrophobic Moment 0.47

Boman Index0.27

Instability Index-13.72

Aliphatic Index 97.50

Aromaticity 0.2500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 208.15

LogP -1.05

H-bond Donors 7.0

H-bond Acceptors 7.0

Rotatable Bonds 12.0

Heavy Atoms 33.0

Ring Count 1.0

Amide Bonds 3.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0053671 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory

TargetCaspase 1 (Human)

RECORD: Rec_0425794 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Familyprotein-binding peptide

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Protein-binding Peptide-protein interaction Structural binding

TargetPDB 3IBC receptor chain B

MethodProtein-peptide complex structure