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MYP_030708
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Basic Information
3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibiotic activity
not Standard
29 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GKGLXXGLXXGKXXGLXXGKXXGLXXGLR
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0034289 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
tetrahydroisoquinolinecarboxylic acid, B = octahydroindolecarboxylic acid, C terminal -CONH2 at 5,9,13,17,21,25; non-canonical residue code at 6,10,14,18,22,26; tetrahydroisoquinolinecarboxylic acid, B = octahydroindolecarboxylic acid, C terminal -CONH2
Bio-Activity Profile
Antimicrobial Antibacterial
MIC against Salmonella typhimurium
PMID17547385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17547385/
RECORD: Rec_0045146 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Tic= tetrahydroisoquinolinecarboxylic acid, Oic= octahydroindolecarboxylic acid
Bio-Activity Profile
Antimicrobial Antibiotic
Mouse erythrocytes
25 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/17547385/ PMID17547385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17547385/
RECORD: Rec_0301498 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Tic= tetrahydroisoquinolinecarboxylic acid, Oic= octahydroindolecarboxylic acid
Bio-Activity Profile
Antimicrobial Antibiotic
Mouse erythrocytes
100 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/17547385/ PMID17547385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17547385/
RECORD: Rec_0325523 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
tetrahydroisoquinolinecarboxylic acid, B = octahydroindolecarboxylic acid, C terminal -CONH2 at 5,9,13,17,21,25; non-canonical residue code at 6,10,14,18,22,26; tetrahydroisoquinolinecarboxylic acid, B = octahydroindolecarboxylic acid, C terminal -CONH2
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtillis
PMID17547385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17547385/
RECORD: Rec_0328385 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
tetrahydroisoquinolinecarboxylic acid, B = octahydroindolecarboxylic acid, C terminal -CONH2 at 5,9,13,17,21,25; non-canonical residue code at 6,10,14,18,22,26; tetrahydroisoquinolinecarboxylic acid, B = octahydroindolecarboxylic acid, C terminal -CONH2
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ME/GM/MTC resistant bacteria
PMID17547385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17547385/
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