Peptide Database

Peptide NameC20

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC109H198N34O26S

DescriptionStandard

        KKIMRTFLRRISKDILTGKK
    

Molecular Weight2433.02 Da

Isoelectric Point (pI)11.75

Net Charge (pH 7.0)6.76

Net Charge (pH 7.4) 6.55

Charge Density (pH 7.0) 0.3378

GRAVY Index-0.67

Hydrophobic Moment 0.86

Boman Index-0.39

Instability Index47.06

Aliphatic Index 97.50

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1030.01

LogP -7.87

H-bond Donors 39.0

H-bond Acceptors 34.0

Rotatable Bonds 91.0

Heavy Atoms 170.0

Ring Count 1.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0419261 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli ATCC 25922

Activity16 μg/mL

MethodMIC

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