Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC925H1402N208O282S10

DescriptionStandard

        VDDLTEVDYSLNSLPAIFQPFIDLDLKGMVFPAGNYTGSPYVAVPFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNMTIAEDTCSYFNINTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIISLEQDSFTVDIQGSMEVLAVLPDSTTQSLFTMNIAANTSISLNIFHQKLMGSLCLNR
    

Molecular Weight20268.90 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-14.18

Net Charge (pH 7.4) -14.51

Charge Density (pH 7.0) -0.0775

GRAVY Index0.31

Hydrophobic Moment 0.55

Boman Index0.25

Instability Index41.40

Aliphatic Index 92.73

Aromaticity 0.1311

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7745.75

LogP -82.99

H-bond Donors 262.0

H-bond Acceptors 279.0

Rotatable Bonds 644.0

Heavy Atoms 1425.0

Ring Count 36.0

Amide Bonds 198.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0342032 VERIFIED: NO

Provenance & Taxonomy

OrganismSmithornis capensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria