Peptide Database

Peptide NameInterleukin-6

Function Ontology

Antiviral

Immunology ▸ Chemokine signaling ▸ Chemokine-like peptide

Immunology ▸ Immune modulation ▸ Cytokine modulation

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length187 amino acids

Chemical FormulaC956H1538N266O297S7

DescriptionStandard

        FPTSQVRRGDFTEDTTPNRPVYTTSQVGGLITHVLWEIVEMRKELCNGNSDCMNNDDALAENNLKLPEIQRNDGCYQTGYNQEICLLKISSGLLEYHSYLEYMKNNLKDNKKDKARVLQRDTETLIHIFNQEVKDLHKIVLPTPISNALLTDKLESQKEWLRTKTIQFILKSLEEFLKVTLRSTRQT
    

Molecular Weight21734.50 Da

Isoelectric Point (pI)6.50

Net Charge (pH 7.0)-0.90

Net Charge (pH 7.4) -1.43

Charge Density (pH 7.0) -0.0048

GRAVY Index-0.63

Hydrophobic Moment 0.69

Boman Index-0.12

Instability Index40.88

Aliphatic Index 89.09

Aromaticity 0.0695

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 20190.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 9250.33

LogP -113.78

H-bond Donors 320.0

H-bond Acceptors 307.0

Rotatable Bonds 702.0

Heavy Atoms 1526.0

Ring Count 25.0

Amide Bonds 210.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0415973 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyIL-6 superfamily

Tax ID10090; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide46-52; 75-85

Bio-Activity Profile

Function

Cytokine Growth factor IL-6 superfamily Antiviral Chemokine-like Growth factor signaling Host defense