Peptide Database

Peptide NamePreprofallaxidin-9 [Cleaved into: Fallaxidin-2.1; Fallaxidin-3.2]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC492H774N134O150S4

DescriptionStandard

        MASLKKSLFLVLFLGLVSLSICEEEKRENEEDAEDENHEEESEEKRGLLDFAKHVIGIASKLGKRSEEKRFWPFMGKRSEEKRFWPFMGKRSEE
    

Molecular Weight11094.48 Da

Isoelectric Point (pI)5.36

Net Charge (pH 7.0)-4.28

Net Charge (pH 7.4) -4.67

Charge Density (pH 7.0) -0.0456

GRAVY Index-0.85

Hydrophobic Moment 0.70

Boman Index-0.20

Instability Index92.04

Aliphatic Index 67.45

Aromaticity 0.0957

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4649.35

LogP -39.00

H-bond Donors 163.0

H-bond Acceptors 152.0

Rotatable Bonds 394.0

Heavy Atoms 780.0

Ring Count 15.0

Amide Bonds 95.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0297924 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria fallax [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetB. cereus (Gram-positive)

RECORD: Rec_0305153 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria fallax [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetS. epidermidis (Gram-positive)

RECORD: Rec_0318952 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria fallax [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetL. innocua (Gram-positive)

RECORD: Rec_0362324 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria fallax [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

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