Peptide Database

Peptide NameP3

Function Ontology

Anticancer

Anticancer ▸ Anti-proliferative

Anticancer ▸ Apoptosis induction

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide ▸ Cell-penetrating

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC85H130N28O21S

DescriptionStandard

        RRRLREMNWVDYFA
    

Molecular Weight1912.18 Da

Isoelectric Point (pI)10.67

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.56

Charge Density (pH 7.0) 0.1259

GRAVY Index-1.16

Hydrophobic Moment 0.38

Boman Index-0.49

Instability Index80.66

Aliphatic Index 55.71

Aromaticity 0.2143

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 842.93

LogP -5.64

H-bond Donors 32.0

H-bond Acceptors 24.0

Rotatable Bonds 62.0

Heavy Atoms 135.0

Ring Count 4.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0224935 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familyanticancer peptide

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Anti-proliferative Cell-penetrating Apoptosis-inducing

TargetMCF-7; Survivin-IAP interaction

Activity25-40 μM

MethodMTT assay