Peptide Database

Peptide NameHD5(7-32)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC116H201N41O37S4

DescriptionStandard

        TGRCATRESLSGVCEISGRLYRLCCR
    

Molecular Weight2890.35 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)2.36

Net Charge (pH 7.4) 2.11

Charge Density (pH 7.0) 0.0909

GRAVY Index-0.15

Hydrophobic Moment 0.69

Boman Index-0.22

Instability Index14.66

Aliphatic Index 75.00

Aromaticity 0.0385

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1296.30

LogP -17.28

H-bond Donors 54.0

H-bond Acceptors 44.0

Rotatable Bonds 97.0

Heavy Atoms 198.0

Ring Count 1.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0290522 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

TargetPseudomonas aeruginosa ATCC 27853

Activity50 μM

MethodMIC

RECORD: Rec_0310932 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEnterococcus faecium 475747

Activity100 μM

MethodMIC

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