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MYP_030486
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Basic Information
HD5(7-32)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
26 amino acids
C116H201N41O37S4
Standard
Sequence
TGRCATRESLSGVCEISGRLYRLCCR
Physicochemical Analysis
2890.35 Da
8.96
2.36
2.11
0.0909
-0.15
0.69
-0.22
14.66
75.00
0.0385
1490.00
1740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1296.30
-17.28
54.0
44.0
97.0
198.0
1.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0016737 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
100 μM
MIC
PMID30808760 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30808760/
RECORD: Rec_0085989 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii 4-MRGN
100 μM
MIC
PMID30808760 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30808760/
RECORD: Rec_0143927 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPatent WO 2020/144166 A1 Evidence URLhttps://patents.google.com/patent/WO2020144166A1/en PatentWO 2020/144166 A1
RECORD: Rec_0216731 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
E. faecium 475747
25 μM
MIC
PaperPaneth cell alpha-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments
RECORD: Rec_0242113 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Acinetobacter baumannii 4-MRGN
25 μM
MIC
PaperPaneth cell alpha-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments
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