Peptide Database

Peptide NameRugosin-RN antimicrobial peptide

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC370H610N94O118S6

DescriptionStandard

        MFTMKKSLLFLFFLGTISLSFCEEERSADEDDEGEMTEEEKRSIRDKIKTIAIDLAKSAGTGVLKTLICKLNKSC
    

Molecular Weight8455.75 Da

Isoelectric Point (pI)5.12

Net Charge (pH 7.0)-2.51

Net Charge (pH 7.4) -2.80

Charge Density (pH 7.0) -0.0334

GRAVY Index-0.17

Hydrophobic Moment 0.74

Boman Index-0.03

Instability Index44.38

Aliphatic Index 87.20

Aromaticity 0.0667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3464.88

LogP -32.30

H-bond Donors 125.0

H-bond Acceptors 122.0

Rotatable Bonds 302.0

Heavy Atoms 588.0

Ring Count 5.0

Amide Bonds 75.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0053268 VERIFIED: NO

Provenance & Taxonomy

OrganismSylvirana [Animal]

Tax ID1659747

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal