Peptide Database

Peptide NameHellethionin A

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC196H317N67O66S8

DescriptionStandard

        KSCCRNTLGRNCYNGCRFTGGSQPTCGRLCDCIHVTTTTCPSSHPS
    

Molecular Weight4924.54 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)3.85

Net Charge (pH 7.4) 3.43

Charge Density (pH 7.0) 0.0838

GRAVY Index-0.52

Hydrophobic Moment 0.65

Boman Index-0.14

Instability Index46.85

Aliphatic Index 31.74

Aromaticity 0.0435

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2150.08

LogP -35.58

H-bond Donors 85.0

H-bond Acceptors 80.0

Rotatable Bonds 154.0

Heavy Atoms 337.0

Ring Count 7.0

Amide Bonds 49.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0004454 VERIFIED: NO

Provenance & Taxonomy

OrganismHelleborus purpurascens [Plant]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-40; 4-32; 12-30; 16-26

Bio-Activity Profile

Function

Toxin

TargetIt seems to exert

RECORD: Rec_0064342 VERIFIED: YES