Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC338H550N92O87S8

DescriptionStandard

        MKTFLLTLVVLLLLSQAIPGNTERCWRQRGSCREKCTKDEKFYVFCLSGKVCCVKPKYMPNLPHK
    

Molecular Weight7551.07 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)7.53

Net Charge (pH 7.4) 7.15

Charge Density (pH 7.0) 0.1158

GRAVY Index-0.12

Hydrophobic Moment 0.58

Boman Index-0.04

Instability Index52.68

Aliphatic Index 83.85

Aromaticity 0.0923

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2894.42

LogP -22.56

H-bond Donors 107.0

H-bond Acceptors 104.0

Rotatable Bonds 252.0

Heavy Atoms 525.0

Ring Count 12.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0201301 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence