Peptide Database

Peptide NameS-type Pyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length552 amino acids

Chemical FormulaC2567H4012N706O819S13

DescriptionStandard

        MPGFSYDGDSGGSEVRIDITCGMDRGSDGNWHSSCVDDGSGYNGGGGNNSGSGANPVDPYNPDINTVGMSVSHGRQGYWGYRLISGDDKNNYYLKIFVPYGDSEAAKFAKASQDLLDAVQAEEAAKKAAEAASSEDKAAAEEAAAAAEQARENAELEQQKQQRLAAQARLFSQDIQAVRGIAVTSGIEASPVSFALAGLGGISYTGTPAAVIHSRLMAAFAWLYRIATASIVGPVTAVVTALFYTPSVGVGSDLVPGRDVSAMIPGDTMGLPDVSELEKAYETGTPVAMPVRGSLDMDEENKLSLNLVRSPVTGSVNVAKAVKDEQTGYYSYALPDIPGVPRQTILISPADAPGVNGPTALTGPVALPELVVSTGDYDGDGTVPTNDVLPTPWPLDNDFNDIILIFPPDSGLRPIYVMFRSPRNMPGTVGGKGKSVGDNWLGGASEGEGAPIPKQVADKLRGKTYSSFDSFRRALWKAVGADPDLSKQFNSYDIEVLKKGHAPLALFKDAAGKRIKMELHHKTEISNGGDVYNVDNLNIVTPKRHIEIHKGE
    

Molecular Weight58284.40 Da

Isoelectric Point (pI)4.90

Net Charge (pH 7.0)-19.74

Net Charge (pH 7.4) -20.54

Charge Density (pH 7.0) -0.0358

GRAVY Index-0.29

Hydrophobic Moment 0.68

Boman Index0.06

Instability Index40.44

Aliphatic Index 78.68

Aromaticity 0.0725

Extinction Coeff. Reduced 62800.00

Extinction Coeff. Oxidized 62925.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0345248 VERIFIED: YES

Provenance & Taxonomy

OrganismKosakonia oryziphila [Animal]

FamilyColicin/Pyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)