Peptide Database

Peptide NameRNS6_NICAL

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Neurological / Signaling ▸ Signaling peptide

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length215 amino acids

Chemical FormulaC1127H1719N287O311S16

DescriptionStandard

        GYKYTVQKINNTIKTVTKGYPNLSCTKGQELWFVGICFDSTAKNVIDCPNKTQNFWRREYIKHGTCCSEIYNQVQYFRLAMALKDKFDLLTSLKNHGIIRMFNLPLTSVFVIFLFALSPIYGAFEYMQLVLQWPTAFCHTTPCKNIPSNFPKTCKTASNQGIMFPTIHGLWPDNVSTTLNFCGKEDDYNIIMDGPEKNGLYVRWPDLIREKADCM
    

Molecular Weight24777.48 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)6.01

Net Charge (pH 7.4) 5.40

Charge Density (pH 7.0) 0.0280

GRAVY Index-0.20

Hydrophobic Moment 0.66

Boman Index0.07

Instability Index30.41

Aliphatic Index 77.07

Aromaticity 0.1349

Extinction Coeff. Reduced 42400.00

Extinction Coeff. Oxidized 43025.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0159645 VERIFIED: YES

Provenance & Taxonomy

OrganismNicotiana alata [Plant]

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Signaling Enzyme inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme