Peptide Database

Peptide NameDermaseptin-1 (DStar 01)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC132H225N37O39

DescriptionStandard

        GLWSKIKETGKEAAKAAGKAALNKIAEAV
    

Molecular Weight2954.42 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.0953

GRAVY Index-0.20

Hydrophobic Moment 0.61

Boman Index0.03

Instability Index8.42

Aliphatic Index 91.38

Aromaticity 0.0345

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1245.48

LogP -11.79

H-bond Donors 43.0

H-bond Acceptors 42.0

Rotatable Bonds 105.0

Heavy Atoms 208.0

Ring Count 2.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0424898 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa tarsius [Animal]

FamilyDermaseptin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Antifungal

TargetCandida albicans and Paracoccidioides brasiliensis

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