Peptide Database

Peptide NameC-terminal Filaggrin-2 derived peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC131H180N38O43

DescriptionStandard

        RHGGQSGLVWKHGSYGSEDYDYGQSGF
    

Molecular Weight2975.06 Da

Isoelectric Point (pI)6.00

Net Charge (pH 7.0)-1.06

Net Charge (pH 7.4) -1.38

Charge Density (pH 7.0) -0.0394

GRAVY Index-1.20

Hydrophobic Moment 0.38

Boman Index-0.06

Instability Index62.95

Aliphatic Index 25.19

Aromaticity 0.1852

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1320.68

LogP -16.43

H-bond Donors 47.0

H-bond Acceptors 44.0

Rotatable Bonds 95.0

Heavy Atoms 212.0

Ring Count 8.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0074782 VERIFIED: YES

Provenance & Taxonomy

OrganismSaimiri boliviensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)