Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length507 amino acids

Chemical FormulaC2571H3987N641O743S15

DescriptionStandard

        MHTKTVGVLWGCFFLWNLYTSSAQTIYPGIKARATQRALDYGVQAGMEMIEQMLKEKNIPDLKGSESLEFLKVDYVNYNFSNIKINAFSFPNTSLAFVPGVGIKALTNHGTANISTNWEIKSPLFQDTGGADLFLSGVYFTGIIVLARNDFGHPILKLQDCYAQVNHAHVSFSGELSVLYNSFAEPMEKPILKNLNEMLCPIIMNEVEALNANLSTIEVLTKIDNYTLLDYSLISSPEITENYIDLNLKGVVYPLEDLTDPPFSPVPFVLPERSDSMLYVGISEFFFKSASFAYFTAGAFNVTLSTKEISNHLVQNSQGVGNVLSRIAEIYILSQPFLVRVMATEPPVISLLPGNFTLDIPASIMILTQSKNSTAEAIVSMDFVASTSVGLVILGQRLVCSLSLNRFRLSLPESNRSNIEVLRFENILSSILHFGILPLANAKLQQGFPLPNPHKISFVNSDIEVFEGFLLISTDLKYETSLKQQPSFHGWEGLNFINGQWRGKPAA
    

Molecular Weight56244.98 Da

Isoelectric Point (pI)5.29

Net Charge (pH 7.0)-11.69

Net Charge (pH 7.4) -12.54

Charge Density (pH 7.0) -0.0231

GRAVY Index0.15

Hydrophobic Moment 0.67

Boman Index0.18

Instability Index37.70

Aliphatic Index 102.29

Aromaticity 0.1065

Extinction Coeff. Reduced 51340.00

Extinction Coeff. Oxidized 51590.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0059464 VERIFIED: NO

Provenance & Taxonomy

OrganismPanthera pardus (Leopard) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria