Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length158 amino acids

Chemical FormulaC789H1242N230O237S4

DescriptionStandard

        MVEINNQRKAFLDMLAWSEGTDNGRQKTRNHGYDVIVGGELFTDYSDHPRKLVTLNPKLESTAAGRYQLLSRWWDAYRKQLGLKDFSPKSQDAVALQQIKERGALPMIDRGDIRQAIDRCSNIWASLPGAGYGQFEHKADSLITKFKEAGGTVREIDV
    

Molecular Weight17869.96 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)1.77

Net Charge (pH 7.4) 1.34

Charge Density (pH 7.0) 0.0112

GRAVY Index-0.63

Hydrophobic Moment 0.68

Boman Index-0.11

Instability Index25.02

Aliphatic Index 77.85

Aromaticity 0.0886

Extinction Coeff. Reduced 29450.00

Extinction Coeff. Oxidized 29450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7620.77

LogP -77.36

H-bond Donors 266.0

H-bond Acceptors 246.0

Rotatable Bonds 604.0

Heavy Atoms 1260.0

Ring Count 26.0

Amide Bonds 172.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0250105 VERIFIED: YES

Provenance & Taxonomy

OrganismShigella phage Sf6 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic