Peptide Database

Peptide NameDefensin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC461H751N131O134S9

DescriptionStandard

        MVKIYFLAALLLVAVAATMSLPLGEEEHSLIPIFNEERADRQRRVTCDLLSIKGVAEHSACAANCLSMGKAGGRCENGICLCRTTTFKELWDKRFG
    

Molecular Weight10561.28 Da

Isoelectric Point (pI)7.60

Net Charge (pH 7.0)0.64

Net Charge (pH 7.4) 0.21

Charge Density (pH 7.0) 0.0066

GRAVY Index0.16

Hydrophobic Moment 0.52

Boman Index0.06

Instability Index39.42

Aliphatic Index 95.62

Aromaticity 0.0625

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4251.98

LogP -39.83

H-bond Donors 156.0

H-bond Acceptors 146.0

Rotatable Bonds 356.0

Heavy Atoms 735.0

Ring Count 11.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0389966 VERIFIED: NO

Provenance & Taxonomy

OrganismHabropoda laboriosa [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence