Peptide Database

Peptide NameDox-pVEC-gHo (Dox- gHoPe2)

Function Ontology

Anticancer

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC161H270N60O40S2

DescriptionStandard

        CLLIILRRRIRKQAHAHSKNHQQQNPHQPPM
    

Molecular Weight3750.37 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)6.10

Net Charge (pH 7.4) 5.67

Charge Density (pH 7.0) 0.1967

GRAVY Index-1.15

Hydrophobic Moment 0.58

Boman Index-0.35

Instability Index88.91

Aliphatic Index 81.94

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1646.17

LogP -17.29

H-bond Donors 56.0

H-bond Acceptors 52.0

Rotatable Bonds 126.0

Heavy Atoms 263.0

Ring Count 7.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0094547 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCyclization

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic

RECORD: Rec_0101219 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCyclization

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

RECORD: Rec_0147264 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilypVEC

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermSuccinimidyl-4-(N-mal-eimidomethyl) cyclohexane-1-carboxylate (SMCC)

C-TermAmidation

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery

RECORD: Rec_0433231 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Structure & Mods

Bio-Activity Profile

Function

Tumor homing Cell-penetrating Glioma targeting

TargetU87 human glioma cells

Activityefficient uptake qualitative

Methodcellular uptake assay (fluorescence imaging)

RECORD: Rec_0433232 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Structure & Mods

Bio-Activity Profile

Function

Tumor homing Glioma targeting Anticancer drug delivery

Targetmouse glioma xenograft tumors

Activityselective tumor labeling; enhanced doxorubicin efficacy vs free drug qualitative

Methodin vivo tumor targeting and antitumor efficacy assay