Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length198 amino acids

Chemical FormulaC986H1544N246O277S9

DescriptionStandard

        GEFYNIGKHQEPPFSPAVFSLPPQINNMLYIGVSSFTFESAAFVYNTAGALSLDITDDMIPKISPVRLNTRTFGVFIPQIAKRFPGLMMKLLVKMSKAPVITFEPNNATVQSFASMTAYAIQPNAALTPLFVLNLVSSVSARVFVSGMRLAGAVTLNKMDLTLGTSDVGDFHVSTLNSIFQTVLNFVVIPRMNGEYSL
    

Molecular Weight21564.87 Da

Isoelectric Point (pI)8.97

Net Charge (pH 7.0)1.94

Net Charge (pH 7.4) 1.61

Charge Density (pH 7.0) 0.0098

GRAVY Index0.37

Hydrophobic Moment 0.64

Boman Index0.23

Instability Index40.44

Aliphatic Index 96.97

Aromaticity 0.1061

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8261.38

LogP -104.23

H-bond Donors 279.0

H-bond Acceptors 290.0

Rotatable Bonds 690.0

Heavy Atoms 1518.0

Ring Count 37.0

Amide Bonds 216.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0166743 VERIFIED: NO

Provenance & Taxonomy

OrganismNotothenia coriiceps [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria