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MYP_030254
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Basic Information
P-113
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Antiviral
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-aging
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-wrinkle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C71H109N27O14
Standard
Sequence
AKRHHGYKRKFH
Physicochemical Analysis
1564.80 Da
11.17
5.05
4.71
0.4211
-2.28
0.38
-0.68
63.83
8.33
0.1667
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
691.55
-5.62
26.0
22.0
53.0
112.0
5.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0275332 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Amphibian skin peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Cytotoxic
U-937
0.5 μg/mL
Cytotoxicity assay
PMID16512752;21403917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16512752/
RECORD: Rec_0282065 VERIFIED: YES
Provenance & Taxonomy
Insecta [Animal]; Candida albicans [Animal]
50557; 33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID16512752 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16512752/
RECORD: Rec_0283242 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Histatin-derived
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiofilm Antibacterial
Streptococcus mutans
25, 50 μM
Crystal violet assay
RECORD: Rec_0300798 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans HIV pt. isolate 162 (
0.8 μg/mL
MIC
PMID11302797;28851350 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11302797/
RECORD: Rec_0340927 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans HIV pt. isolate 162 (
3.1 μg/mL
MIC
PMID11302797;28851350 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11302797/
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