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MYP_030254
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Basic Information
P-113
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Antiviral
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-aging
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-wrinkle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C71H109N27O14
Standard
Sequence
AKRHHGYKRKFH
Physicochemical Analysis
1564.80 Da
11.17
5.05
4.71
0.4211
-2.28
0.38
-0.68
63.83
8.33
0.1667
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
691.55
-5.62
26.0
22.0
53.0
112.0
5.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0070330 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Histatin
9606
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
All-D amino-acid analogue
Bio-Activity Profile
Antifungal
nonmucoid Pseudomonas aeruginosa ATCC 27853
1.25 μg/mL
LD90
PaperP-113D, an Antimicrobial Peptide Active againstPseudomonas aeruginosa, Retains Activity in the Presence of Sputum from Cystic Fibrosis Patients.Antimicrob. Agents Chemother.(2001) PMID11709321 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11709321/
RECORD: Rec_0079352 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans HIV pt. isolate 162 (
3.1
MIC
PMID11302797;28851350 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11302797/
RECORD: Rec_0087775 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans HIV pt. isolate 84
3.1 μg/mL
MIC
PMID11302797;28851350 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11302797/
RECORD: Rec_0089957 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans ATCC 44505
3.1 μg/mL
MIC
PMID11302797;28851350 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11302797/
RECORD: Rec_0097034 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans HIV pt. isolate 118
3.1 μg/mL
MIC
PMID11302797;28851350 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11302797/
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