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MYP_030234
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
9 amino acids
C45H71N13O12
Standard
Sequence
YANPAVVRP
Physicochemical Analysis
986.12 Da
8.75
0.76
0.55
0.0843
-0.06
0.33
0.07
74.80
86.67
0.1111
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
403.76
-3.27
13.0
13.0
25.0
70.0
3.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0029237 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
kappa-Casein-derived
9606
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
7.8 μM
IC50
PaperInhibition of angiotensin-converting enzyme by synthetic peptide fragments of human kappa-casein | Kohmura, M. et al. | DOI: 10.1080/00021369.1989.10869621 Evidence URLhttps://www.uniprot.org/uniprotkb/P07498/entry
RECORD: Rec_0060053 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]; Homo sapiens [Animal]
9913; 9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperQSAR study on angiotensin-converting enzyme inhibitor oligopeptides based on a novel set of sequence information descriptors PMID20941517 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20941517/
RECORD: Rec_0074079 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
7.8
IC50
PaperKohmura M., Nio N., Kubo K., Minoshima Y., Munekata E., Ariyoshi Y.. Inhibition of angiotensin-converting enzyme by synthetic peptides of human b-casein. Agric. Biol. Chem., 53, 2107-2114.
RECORD: Rec_0322739 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
0.89 pIC50
pIC50
PaperQSAR study on angiotensin-converting enzyme inhibitor oligopeptides based on a novel set of sequence information descriptors. PMID20941517 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20941517/
RECORD: Rec_0330995 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
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