Peptide Database

Peptide NameSLAY-screened peptide P4480

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC97H157N33O26S

DescriptionStandard

        PPSSRSHHRRLPASCLATFI
    

Molecular Weight2233.55 Da

Isoelectric Point (pI)11.70

Net Charge (pH 7.0)3.12

Net Charge (pH 7.4) 2.95

Charge Density (pH 7.0) 0.1561

GRAVY Index-0.38

Hydrophobic Moment 0.41

Boman Index-0.13

Instability Index149.99

Aliphatic Index 68.50

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 928.86

LogP -11.53

H-bond Donors 36.0

H-bond Acceptors 32.0

Rotatable Bonds 67.0

Heavy Atoms 157.0

Ring Count 6.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0320313 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/