Peptide Database

Peptide NameCycloviolacin H2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC127H209N39O39S6

DescriptionStandard

        CAESCVYIPCTVTALLGCSCRNRVCYRN
    

Molecular Weight3098.65 Da

Isoelectric Point (pI)8.34

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.41

Charge Density (pH 7.0) 0.0608

GRAVY Index0.42

Hydrophobic Moment 0.34

Boman Index0.02

Instability Index42.09

Aliphatic Index 80.00

Aromaticity 0.0714

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1270.79

LogP -15.60

H-bond Donors 52.0

H-bond Acceptors 47.0

Rotatable Bonds 96.0

Heavy Atoms 211.0

Ring Count 3.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0252185 VERIFIED: YES

Provenance & Taxonomy

OrganismChassalia chartacea [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)