Peptide Database

Peptide NameThiocillin GE37468 (Antibiotic GE37468)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC255H385N65O92S7

DescriptionStandard

        MGNNEEYFIDVNDLSIDVFDVVEQGGAVTALTADHGMPEVGASTNCFCYICCSCSSN
    

Molecular Weight6057.62 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-9.45

Net Charge (pH 7.4) -9.80

Charge Density (pH 7.0) -0.1657

GRAVY Index0.18

Hydrophobic Moment 0.45

Boman Index0.19

Instability Index29.21

Aliphatic Index 71.75

Aromaticity 0.0877

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2509.35

LogP -31.22

H-bond Donors 88.0

H-bond Acceptors 91.0

Rotatable Bonds 194.0

Heavy Atoms 419.0

Ring Count 7.0

Amide Bonds 62.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0084109 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptomyces sp [Bacterium]

FamilyThiocillin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Anti-MRSA Anti-Gram-positive Non-hemolytic

TargetBacillus subtilis (Gram-positive)

RECORD: Rec_0309961 VERIFIED: YES