Peptide Database

Peptide NameThionin NsW1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC160H275N53O46S8

DescriptionStandard

        KSCCKNTLGRNCYNTCRFMKKPRKTCSGLCGCKIS
    

Molecular Weight3933.74 Da

Isoelectric Point (pI)9.67

Net Charge (pH 7.0)8.68

Net Charge (pH 7.4) 8.37

Charge Density (pH 7.0) 0.2481

GRAVY Index-0.62

Hydrophobic Moment 0.65

Boman Index-0.30

Instability Index10.15

Aliphatic Index 33.43

Aromaticity 0.0571

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1656.63

LogP -22.82

H-bond Donors 67.0

H-bond Acceptors 63.0

Rotatable Bonds 136.0

Heavy Atoms 267.0

Ring Count 3.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0019672 VERIFIED: NO

Provenance & Taxonomy

OrganismNigella sativa [Plant]

FamilyThionin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Defense peptide Anti-Candida Cytolytic Toxin Non-hemolytic

TargetNo Target Organism Found

RECORD: Rec_0187537 VERIFIED: NO