Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length117 amino acids

Chemical FormulaC603H925N171O167S9

DescriptionStandard

        MRIFAFIFAAFILLAQIFSGRAGFYRSQYCQKMDGRCEIECLSFEVKIGGCRSDLTPLCCKRLSRIRFNLQRHPYSGYGDQQTLRQNVNCWHELEILKYKYNTTFNSGNLTNGFGGS
    

Molecular Weight13530.43 Da

Isoelectric Point (pI)9.23

Net Charge (pH 7.0)6.61

Net Charge (pH 7.4) 6.17

Charge Density (pH 7.0) 0.0565

GRAVY Index-0.25

Hydrophobic Moment 0.53

Boman Index-0.02

Instability Index50.36

Aliphatic Index 72.56

Aromaticity 0.1453

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14815.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5529.62

LogP -54.48

H-bond Donors 202.0

H-bond Acceptors 185.0

Rotatable Bonds 451.0

Heavy Atoms 950.0

Ring Count 22.0

Amide Bonds 130.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0017341 VERIFIED: NO

Provenance & Taxonomy

OrganismErinaceus europaeus [Animal]

FamilyBeta-defensin; Defensin

Tax ID9365

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic