Peptide Database

Peptide NameNukacin ISK-1

Function Ontology

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Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC125H181N33O35S5

DescriptionStandard

        DGVFRTISHECHMNTWMFIFTCCS
    

Molecular Weight2866.30 Da

Isoelectric Point (pI)5.99

Net Charge (pH 7.0)-1.09

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.0455

GRAVY Index0.27

Hydrophobic Moment 0.51

Boman Index0.19

Instability Index41.54

Aliphatic Index 44.58

Aromaticity 0.1667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1086.51

LogP -9.79

H-bond Donors 42.0

H-bond Acceptors 41.0

Rotatable Bonds 89.0

Heavy Atoms 198.0

Ring Count 7.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0347590 VERIFIED: YES

Provenance & Taxonomy

OrganismButyrivibrio fibrisolvens [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)