Peptide Database

Peptide NameCrotamine

Function Ontology

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Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC167H257N49O42S5

DescriptionStandard

        YKRCHKKGGHCFPKEKICIPPSSDFGKMDCRW
    

Molecular Weight3783.46 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)4.89

Net Charge (pH 7.4) 4.52

Charge Density (pH 7.0) 0.1529

GRAVY Index-1.02

Hydrophobic Moment 0.59

Boman Index-0.25

Instability Index82.27

Aliphatic Index 24.38

Aromaticity 0.1250

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1464.71

LogP -12.41

H-bond Donors 55.0

H-bond Acceptors 54.0

Rotatable Bonds 124.0

Heavy Atoms 263.0

Ring Count 10.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0298965 VERIFIED: YES

Provenance & Taxonomy

OrganismCrotalus oreganus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)