Peptide Database

Peptide NameDermaseptin-DA2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC371H614N100O121S3

DescriptionStandard

        MALVKKSLFLVLFLGLVSLSICEEKRENEDEEEQEDDEQSEEKRALWKTLLKKVGKVAGKAVLNAVTNMANQNEQ
    

Molecular Weight8507.64 Da

Isoelectric Point (pI)4.83

Net Charge (pH 7.0)-4.48

Net Charge (pH 7.4) -4.75

Charge Density (pH 7.0) -0.0598

GRAVY Index-0.49

Hydrophobic Moment 0.69

Boman Index-0.10

Instability Index54.91

Aliphatic Index 97.47

Aromaticity 0.0400

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3659.18

LogP -34.26

H-bond Donors 123.0

H-bond Acceptors 120.0

Rotatable Bonds 307.0

Heavy Atoms 595.0

Ring Count 4.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0413905 VERIFIED: NO

Provenance & Taxonomy

OrganismAgalychnis dacnicolor [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-negative bacteria; Gram-positive bacteria

MethodQualitative functional evidence