Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length157 amino acids

Chemical FormulaC787H1185N177O239S8

DescriptionStandard

        QGIVYPGGNYSAPPFVAAPFAVPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITITEETCSYFNISTEIFGSVIPEVAQYSVTPYPVMLKLMATETPIISLQQDSFTIEIQGSMEVFAVLPDSSTQLLFTMSIAANTSIAVNIFDQKLMGSLCLNR
    

Molecular Weight17206.39 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-10.24

Net Charge (pH 7.4) -10.51

Charge Density (pH 7.0) -0.0652

GRAVY Index0.36

Hydrophobic Moment 0.48

Boman Index0.28

Instability Index55.70

Aliphatic Index 87.01

Aromaticity 0.1401

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6569.41

LogP -61.21

H-bond Donors 223.0

H-bond Acceptors 237.0

Rotatable Bonds 541.0

Heavy Atoms 1211.0

Ring Count 32.0

Amide Bonds 171.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0403599 VERIFIED: NO

Provenance & Taxonomy

OrganismCrypturellus soui [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria