MYP_029995
Wollamide B [l3D-Me-Leu, N5Me-Asn]
Anticancer
Antimicrobial
Antimicrobial
▸
Antibacterial
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
not Standard
6 amino acids
-
contains X representing unresolved or non-standard residue
WLXVXX
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0118683
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
x(3)=METH-Leu; x(5)=METH-Asn; x(6)=D-Orn
Bio-Activity Profile
Antimicrobial
Antibacterial
Human hepatocellular carcinoma HepG2
>100 μM
IC50
RECORD: Rec_0216962
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
x(3)=METH-Leu; x(5)=METH-Asn; x(6)=D-Orn
Bio-Activity Profile
Antimicrobial
Antibacterial
Mycobacterium tuberculosis H37Rv
>80 μM
MIC
RECORD: Rec_0251403
VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
x(3)=METH-Leu; x(5)=METH-Asn; x(6)=D-Orn
Bio-Activity Profile
Antimicrobial
Anticancer
Cytotoxic
RECORD: Rec_0264322
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
x(3)=METH-Leu; x(5)=METH-Asn; x(6)=D-Orn
Bio-Activity Profile
Antimicrobial
Anticancer
HepG2
>100 μM
IC50