Peptide Database

Peptide NamePigment-dispersing factor, Drm-PDH

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Sleep regulation

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC83H141N23O30S

DescriptionStandard

        NSELINSLLSLPKNMNDA
    

Molecular Weight1973.21 Da

Isoelectric Point (pI)4.37

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.0687

GRAVY Index-0.31

Hydrophobic Moment 0.51

Boman Index0.01

Instability Index30.84

Aliphatic Index 113.89

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 882.90

LogP -10.90

H-bond Donors 28.0

H-bond Acceptors 30.0

Rotatable Bonds 67.0

Heavy Atoms 137.0

Ring Count 1.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0033970 VERIFIED: NO

Provenance & Taxonomy

OrganismDrosophila melanogaster [Animal]; Drosophila suzukii [Animal]; Glossina morsitans [Animal]

Tax ID7227

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0143240 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila melanogaster [Animal]

FamilyNeuropeptide PDF

Tax ID7227

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Receptor modulation ACE inhibitory Sleep regulation Wake regulation

Targetsmall and large ventral lateral neurons to control sleep and regulates the state transition from sleep to wake (PubMed:19038223, PubMed:19230663)

Half-LifeMammalian: 1.4 hour; Yeast: 3 min; E. coli: >10 hour

RECORD: Rec_0375062 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila melanogaster [Animal]

FamilyNeuropeptide PDF

Tax ID7227

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Receptor modulation ACE inhibitory Sleep regulation Wake regulation

Half-LifeMammalian: 1.4 hour; Yeast: 3 min; E. coli: >10 hour