Peptide Database

Peptide NameTemporin-1Tb (TB) (Temporin-B)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Antiviral

Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Wound healing/Regeneration ▸ Wound healing

Standard StatusStandard

Sequence Length61 amino acids

Chemical FormulaC316H527N85O95S2

DescriptionStandard

        MFTLKKSLLLLFFLGTINLSLCEEERNAEEERRDEPDERDVQVEKRLLPIVGNLLKSLLGK
    

Molecular Weight7101.21 Da

Isoelectric Point (pI)5.08

Net Charge (pH 7.0)-2.49

Net Charge (pH 7.4) -2.74

Charge Density (pH 7.0) -0.0408

GRAVY Index-0.28

Hydrophobic Moment 0.65

Boman Index-0.09

Instability Index42.07

Aliphatic Index 118.20

Aromaticity 0.0492

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2952.45

LogP -22.67

H-bond Donors 102.0

H-bond Acceptors 95.0

Rotatable Bonds 251.0

Heavy Atoms 498.0

Ring Count 5.0

Amide Bonds 64.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0161552 VERIFIED: YES

Provenance & Taxonomy

OrganismRana temporaria [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antiviral Antifungal Anti-HSV Anti-MRSA Antibiofilm Antiparasitic Anti-Gram-positive Hemolytic Synergistic peptide Wound healing

TargetStaphylococcus aureus (Gram-positive)