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MYP_029944
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Basic Information
Dermaseptin-PS2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Wound healing/Regeneration ▸ Wound healing
Standard
28 amino acids
C132H225N37O37S
Standard
Sequence
ALWKTLLKNVGKAAGKAVLNAVTDMVNQ
Physicochemical Analysis
2954.49 Da
10.00
2.79
2.60
0.0998
0.24
0.65
0.14
0.25
115.00
0.0357
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1219.01
-11.22
41.0
41.0
101.0
207.0
2.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000052 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
MRSA
16 μM
MIC
PMID33582221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33582221/
RECORD: Rec_0006601 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
8 μM
MIC
PMID33582221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33582221/
RECORD: Rec_0011103 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
8 μM
MIC
PMID33582221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33582221/
RECORD: Rec_0088647 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
16 μM
MIC
PMID33582221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33582221/
RECORD: Rec_0145928 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
8395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Wound healing
MRSA NCTC 12493
16 μg/mL
MIC
PaperIdentification of new dermaseptins with self-assembly tendency: membrane disruption, biofilm eradication, and infected wound healing efficacy.
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