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MYP_029938
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Basic Information
Enzyme inhibitor 4
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
4 amino acids
C21H36N4O5
Standard
Sequence
IPVP
Physicochemical Analysis
424.53 Da
5.53
-0.24
-0.44
-0.0600
1.38
0.13
0.68
96.60
170.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
133.04
0.57
3.0
5.0
8.0
30.0
2.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0253693 VERIFIED: YES
Provenance & Taxonomy
Hordeum vulgare [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory DPP-IV inhibitory
Dipeptidyl peptidase IV
38.67±5.94 μM
IC50
RECORD: Rec_0299911 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic DPP-IV inhibitory
Dipeptidyl peptidase IV
38.67
IC50
PaperCerme?o M., Connolly A., O¡¯Keeffe M. B., Flynn C., Alashi A. M., Aluko R. E., FitzGerald R. J.. Identification of bioactive peptides from brewers¡¯ spent grain and contribution of Leu/Ile to bioactive potency. J Funct Foods, 60, 103455, 2019.
RECORD: Rec_0374379 VERIFIED: YES
Provenance & Taxonomy
Hordeum vulgare [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
26.20±4.48 μM
IC50