Peptide Database

Peptide NameMauriporin (Non-disulfide-bridged peptide 2.8) (NDBP-2.8)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC383H637N109O99S2

DescriptionStandard

        MNKKTLLVIFFITMLIVDEVNSFKIGGFIKKLWRSKLAKKLRAKGRELLKDYANRVINGGPEEEAAVPAERRR
    

Molecular Weight8416.96 Da

Isoelectric Point (pI)10.39

Net Charge (pH 7.0)8.51

Net Charge (pH 7.4) 8.26

Charge Density (pH 7.0) 0.1166

GRAVY Index-0.26

Hydrophobic Moment 0.79

Boman Index-0.09

Instability Index48.43

Aliphatic Index 102.88

Aromaticity 0.0822

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3422.14

LogP -24.81

H-bond Donors 121.0

H-bond Acceptors 110.0

Rotatable Bonds 296.0

Heavy Atoms 593.0

Ring Count 9.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0171518 VERIFIED: NO

Provenance & Taxonomy

OrganismAndroctonus mauritanicus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Toxin Anticancer Cytotoxic Non-hemolytic